The use of oral antibiotics can be used as a next step from topical agents such as benzoyl peroxide and retinoid creams, gels and lotions. Antibiotic therapy is good for inflammatory acne and has been shown to be very effective in some patients.health

In the clinical world, oral antibiotic acne therapy is usually referred to as systemic antibacterial treatment. The word systemic implies that the antibiotics travel around the blood stream; not only to the sites where there is acne, but to sites where acne is not present.

Broadly speaking, oral antibiotic acne drugs can be divided into 3 maily names:
1.Cyclines
2.Macrolides
3.Sulphonamides

Common side effects of antibiotics used for acne management:

Cyclines:
1.Nausea
2.Vomiting
3.Diarrhoea

Macrolides (Erythromycin):
1.Nausea
2.Vomiting
3.Abdominal discomfort
4.Rashes
5.Reversible hearing loss

Sulphonamides (Trimethoprim)
1.Gastro-intestinal disturbances
2.Nausea
3.Vomiting
4.Itchiness and rashes

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